De Armas has been married once to the Spanish actor Marc Clotet from 2011 to 2013. The Cuban actress was only 22 when she tied the knot and it came well before her Hollywood breakthrough in the late 2010s. She dated Ben Affleck after meeting the actor while filming Deep Water in 2019. They are said to have split up in 2021.

Tom Cruise and Ana de Armas just made their romance official, and the timing could not be more dramatic. On July 30, 2025, the couple confirmed to People magazine that they are dating. The news dropped less than twenty‑four hours after Ana was slammed online for liking a post on Instagram that made fun

"Top Gun" star Tom Cruise has been linked to Cher, Penélope Cruz and Melissa Gilbert, along with his three marriages.