Objective To identify risk factors for asthma attacks and poor asthma control in children aged 5–16 years. Methods Prospective observational cohort study of 460 children with asthma or suspected ...

The median life expectancy for cystic fibrosis is now over 30 years, and it is projected that in newborn infants it will become more than 40 years. The identification of the cystic fibrosis gene and ...

Objective We aimed to measure the prevalence and incidence of latent tuberculosis infection (LTBI) and tuberculosis (TB) disease in children in close contact with patients with drug-resistant TB ...

We encounter, occasionally, parents who are incapable of making medical decisions on behalf of their incompetent or ...

The hierarchy of evidence in assessing the effectiveness of interventions or treatments is explained, and the gold standard for evaluating the effectiveness of interventions, the randomised controlled ...

Background: Coeliac disease (CD) is a disorder that may depend on genetic, immunological, and environmental factors. Recent observational studies suggest that breast feeding may prevent the ...

Aim DRC software aims to reduce dosing errors,1 however, it has been linked to ‘alert fatigue’, a phenomenon which causes prescribers to potentially override alerts despite being clinically relevant.2 ...

Results Under-recognition was the highest in the lowest income quintile, with 11.5% of children from the lowest income quintile families who scored in the clinical range on the SDQ perceived by ...

Objectives Historically diagnoses of Trisomy 13 (T13) and Trisomy 18 (T18) have been associated with a very poor prognosis. Median survival of full T18 is 14days, T13 is 10days and 3-month survival is ...

With the growing number of children and young people with complex care needs or life-limiting conditions, alternative routes for nutrition have been established (such as gastrostomy feeding). The ...

Objectives To describe the range of concurrent cardiac malformations in biliary atresia (BA) while providing a functional framework of risk. Methods Demographic and variables were collected from a ...

Background Over the last few years, there has been increasing attention to the involvement of the central nervous system in Duchenne muscular dystrophy (DMD). The aim of this study was to assess the ...