This PhD project investigates how muscle stem cells regenerate in health and disease, aiming to uncover molecular mechanisms and develop targeted therapies for neuromuscular disorders. Skeletal muscle ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The bioenergetic requirements of muscle stem ...

The 2020 Nobel Prize in Chemistry was awarded for the development of CRISPR/Cas9, a method also known as "gene scissors," which enables researchers to better understand how human cells function and ...

The glycocalyx surrounds each cell in the human body like a coat. This complex sugar layer plays a key role in the progression of numerous diseases, such as cancer and autoimmune diseases. The ...

Muscle function and composition are important indicators of age-related health. However, current assessment methods are often complex and expensive, making the early detection of related problems ...

Abstract: Muscles of the human body are composed of tiny actuators made up of myosin and actin filaments. They can exert force in various shapes such as curved or flat, under contact forces and ...

Most in a small group of patients receiving a stem cell-based infusion no longer needed insulin, but the drug may not suit those with more manageable type 1 diabetes. By Gina Kolata A single infusion ...

Department of Radiology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510655, China Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, ...

Bispecific T cell engagers (TcEs) are immunotherapeutic drugs that trigger the destruction of cancer cells by linking T cells to cancer cells through specific surface molecules (antigens). We designed ...

Lymphatic muscle cells (LMCs) are indispensable for lymphatic vessel contraction, and their aberrant recruitment or absence is associated with both primary and secondary lymphedema. Despite their ...