Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. The bioenergetic requirements of muscle stem ...

If we can fully map the structure of our brains, will we be able to understand how they work? That is the goal of researchers attempting to build a wiring diagram, or connectome, of our neural ...

-- Unprecedented improvement compared to baseline and natural history in multiple functional measures including Time to Rise from Floor (TTR), 4-Stair Climb (4SC), Performance of Upper Limb (PUL) and ...

Muscle function and composition are important indicators of age-related health. However, current assessment methods are often complex and expensive, making the early detection of related problems ...

Abstract: Muscles of the human body are composed of tiny actuators made up of myosin and actin filaments. They can exert force in various shapes such as curved or flat, under contact forces and ...

The population across developed countries is getting older and the associated frailty and debilitation are becoming major health problems. This gradual muscle loss is accelerated by the poor capacity ...

Department of Radiology, The Sixth Affiliated Hospital, Sun Yat-sen University, Guangzhou, Guangdong 510655, China Biomedical Innovation Center, The Sixth Affiliated Hospital, Sun Yat-sen University, ...

Bispecific T cell engagers (TcEs) are immunotherapeutic drugs that trigger the destruction of cancer cells by linking T cells to cancer cells through specific surface molecules (antigens). We designed ...

Lymphatic muscle cells (LMCs) are indispensable for lymphatic vessel contraction, and their aberrant recruitment or absence is associated with both primary and secondary lymphedema. Despite their ...

It is well established that cellulose synthesis in higher plants requires three different but related cellulose synthase (CESA) isoforms. Here the authors provide convincing biochemical and cryo ...