The 2025 GenScript Virtual Summit—formerly the Gene and Cell Engineering Summit—serves as a leading international forum for scientists, biotech innovators, and pharmaceutical leaders to examine ...
本研究针对癌症转移过程中EMT(上皮-间质转化)机制研究的局限性,创新性地采用患者来源的细胞外基质(pdECM)培养结直肠癌类器官,通过单细胞多组学技术解析了TNF-α信号通路作为早期转移事件的关键作用,发现AP-1转录复合物通过调控MMP7等靶基因驱动侵袭 ...