Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Mycobacterium tuberculosis causes long-term ...

To help achieve more precise control of gene therapy, engineers have designed a new control circuit that can keep gene expression levels within a target range. The method could be used to deliver ...

Many transcriptional and post-transcriptional mechanisms control gene expression in eukaryotic cells. The zinc finger antiviral protein (ZAP) is induced by interferon and inhibits viral gene ...

The expression of genes has to be carefully regulated in cells; active genes give cells their identity and ability to function. Epigenetic features are just one way that cells control gene expression, ...

Center for Welfare and Social Inclusion of the University of Almeria, Crta. Sacramento s/n, La Cañada de San Urbano 04120, Spain Department of Psychology and Sociology, University of Zaragoza, Crta.

Researchers at the Jackson Laboratory (JAX), the Broad Institute of MIT and Harvard, and Yale University, have used artificial intelligence (AI) to design thousands of new DNA switches that can ...

1 Top Runner Incubation Center for Academia-Industry Fusion, Nagaoka University of Technology, Nagaoka, Japan 2 Department of Mechanical Engineering, Nagaoka University of Technology, Nagaoka, Japan ...

There will be many false hits. You will need to heavily filter the output. For example, if a region is covered by a good alignment, you will want to filter worse alignment. Can I use miniprot for exon ...