Scientists have used 3D models to break down the DNA behavior of cancer cells, in a breakthrough new study which could revolutionize treatment for the disease. Scientists have used 3D models to break ...
In a first, researchers have worked out a way to unravel and model the tangled, 3D structures of intact mammalian genomes from individual cells. The new method, published Monday in Nature, could help ...
DNA replication dynamics in cells from higher eukaryotes follows very complex but highly efficient mechanisms. However, the principles behind initiation of potential replication origins and emergence ...
Scientists have created an unprecedented 3-dimensional structural model of a key molecular "machine" known as the BAF complex, which modifies DNA architecture and is frequently mutated in cancer and ...
DNA can be programmed to self-assemble into high molecular weight 3D assemblies with precise nanometer-scale structural features. Although numerous sequence design strategies exist to realize these ...
An imaging method that reveals a much more diverse and flexible DNA-protein chromatin chain than previously thought has now been developed by researchers. The result suggests a nimbler structure to ...
Current genetic sequencing techniques can provide much information about the genetic makeup and activity in a sample, like a piece of tissue or a drop of blood. But they are unable to reveal where ...