Antibody–siRNA conjugates (ARCs) are a type of promising drug modalities for cancer therapy. However, initial reports of ARCs present the gene knockdown effect only in limited tissues (e.g., muscles) ...

The rapid identification of respiratory virus outbreaks is needed to enable rational and effective public health interventions. We developed new quantitative approaches for simultaneous ...

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Silver nanoparticles (AgNPs) are widely recognized for their unique optical, electronic, and antibacterial properties, enabling their use in biosensing, photonics, electronics, drug delivery, and ...

Plug flow has a huge chemical potential of charge separation at the solid−liquid interface not limited by the Debye length for effectively generating electricity via harvesting energy from rain.

Proton exchange membrane (PEM) water electrolysis offers an efficient route to large-scale green hydrogen production, in which the RuO2 catalyst exhibits superior activity but limited stability.

RNA therapeutics offer a promising approach to cancer treatment by precisely regulating cancer-related genes. While lipid nanoparticles (LNPs) are currently the most advanced nonviral clinically ...

We report an asymmetric total synthesis of (−)-illisimonin A, a sesquiterpene natural product with neurotrophic activity. Illisimonin A possesses a unique cage-like 5/5/5/5/5 pentacyclic scaffold ...

Fluorescence emitters with a multiple-resonant (MR) effect have become a research hotspot. These MR emitters mainly consist of polycyclic aromatic hydrocarbons with boron/nitrogen, nitrogen/carbonyl, ...

The integration of ligand-to-metal charge transfer (LMCT) catalytic paradigms with radical intermediates has transformed the selective functionalization of inert C–H bonds, facilitating the use of ...