DETROIT (AP) Nick Bosa was ready to kick back and relax while the San Francisco 49ers coasted to a season-opening victory. The Detroit Lions made Bosa get back to work.

Yes, some of the luster has rubbed off the Detroit Lions ’ matchup tonight with the San Francisco 49ers. The rematch of January’s NFC championship game — have you heard? — is more for ...

(The 1961 Lions went 6-0-1 on the road, with their tie coming against the 49ers, but went just 2-5 at home at Tiger Stadium.) DAVE BIRKETT'S SCOUTING REPORT: Why I think Lions win NFC title rematch ...

The Detroit Lions capped the first unbeaten road schedule in team history on Monday night in San Francisco. The Lions outgunned the 49ers, 40-34, in the final game of Week 17. With the win, the ...

Lions Detroit Lions nearly come all the way back in 41-33 loss to San Francisco 49ers: Live updates recap Updated: Sep. 12, 2021, 4:25 p.m. | Published: Sep. 12, 2021, 10:42 a.m. 55 1/55 ...

The Lions marched into Santa Clara with an agenda. The winner of this game would not alter the standings for Detroit nor its division, but a victory over the San Francisco 49ers was a year in the ...