"The importance of deoxyribonucleic acid (DNA) within living cells is undisputed" (Watson & Crick, 1953). This opening sentence of James Watson and Francis Crick's second major paper, published ...

Newly developed artificial intelligence (AI) programs accurately predicted the role of DNA's regulatory elements and three-dimensional (3D) structure based solely on its raw sequence, according to ...

This image depicts the chemical structure of cytosine. It shows a hexagonal ring with nitrogen atoms at positions 1 and 3, and a primary amine group attached to carbon 4. The two remaining positions ...

The first crystal structure of an alternative DNA shape from the insulin gene has been revealed. The first crystal structure of an alternative DNA shape from the insulin gene has been revealed by a ...

Tiny tweaks in DNA folding can have big effects. A study from Umeå University shows that even the most subtle changes in DNA’s shape have an important influence on gene activity and energy production.

A change in the DNA sequence of a codon may not change the corresponding amino acid residue in the encoded protein because each residue can be encoded by several codons. This is called the Wobble ...

As one of the inventors of next-generation DNA sequencing, Sir Shankar Balasubramanian could claim to be responsible for a revolution in the life sciences. Balasubramanian and chemist David Klenerman, ...