SportsLine's model simulated Paul Skenes and the Pittsburgh Pirates vs. Chicago Cubs 10,000 times and revealed its MLB picks for Friday afternoon's matchup at Wrigley Field in Chicago

The Pittsburgh Pirates defeated the Chicago Cubs 2-1 in 10 innings on Friday afternoon at Wrigley Field. Paul Skenes took a no-decision after throwing 5.0-shutout innings and Isiah Kiner-Falefa drove in the game-winning run on a sac fly in the top of the 10th.

Pirates ace Paul Skenes struck out five in five scoreless innings. Skenes was matched by Cade Horton, who permitted three hits in 5 2/3 shutout innings.

Our MLB betting picks will toss Matthew Boyd's career splits vs. the Pirates out the window and bank on him shutting down a sorry version of Pittsburgh's offense on Saturday, June 14, 2025.

Rookie Cade Horton matched Pittsburgh Pirates ace Paul Skenes in a pitchers’ duel Friday, but the Chicago Cubs lost 2-1 in 10 innings.

There has been a common theme in the Chicago Cubs' recent losses: an inability to produce with runners on base. It's something the Cubs will look to rectify on Saturday when they host the Pittsburgh Pirates in the third matchup of a four-game set.